Biological circuits underlie most aspects of cell and organismal biology. Circuit biology seeks to understand "mechanisms," the precise structures and interactions of biological parts – be they genes, cells or organisms – that ultimately produce biological function. Circuit biology often involves computational modeling of potential mechanisms, coupled with quantitative tests of the predictions of models by cell biological, molecular biological, and biophysical techniques.
Part of understanding biological systems involves defining the relevant parts and measuring how they change in a quantitative and comprehensive fashion as they carry out their functions. This task is the domain of genomics, proteomics, metabolomics, functional genomics, bioinformatics among other disciplines.
One particularly stunning feature of organisms is their ability to develop from a single fertilized egg; thus, Systems Developmental Biology is an important theme of our program. This theme involves the study of developing organisms by a wide variety of molecular, cellular, and genomic techniques.